Wytheville, Virginia 24382

Wytheville is the countyseat of Wythe County Virginia, the self proclaimed crossroads of Southwest Virginia.
US Post Office -- Wytheville, VIrginia
Wytheville is located near the intersection of Interstates 77 and 81. The town and county was named for George Wythe, a signer of the United States Declaration of Independence and Mentor of Thomas Jefferson. The town is also home to Edith Bolling Wilson, the wife of President Woodrow Wilson.